Description

8-(Pyrimidin-2-Yl)-5,8-Diazaspiro[4.5]Decan-5-Ium Chloride is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic and diazacyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures. It is essential for research and development chemists in the pharmaceutical and biotechnology industries working on innovative drug discovery programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially those targeting the central nervous system (CNS) and oncology.
• Organic Synthesis Building Block: Used to introduce the spiro[4.5]decane and pyrimidine motifs into larger, more complex molecules during medicinal chemistry research.
• Ligand and Catalyst Development: Serves as a structural component for developing novel ligands in catalytic systems or for metal coordination studies.
• Biochemical Research: Employed in the development of chemical probes and tool compounds for studying biological pathways and protein interactions.
• Agrochemical Research: Potential intermediate in the research phase for developing new crop protection agents with specific activity.

Basic Information

Product Name	8-(Pyrimidin-2-Yl)-5,8-Diazaspiro[4.5]Decan-5-Ium Chloride
CAS No.	81461-72-5
Molecular Formula	C13H19ClN4
Molecular Weight	266.77 g/mol
Synonyms	5,8-Diazaspiro[4.5]decan-5-ium, 8-(2-pyrimidinyl)-, chloride (1:1); 8-(2-Pyrimidinyl)-5,8-diazaspiro[4.5]decan-5-ium chloride; Spiro[4.5]decane-8,5'-pyrimidine derivative; 2-(5,8-Diazaspiro[4.5]decan-8-yl)pyrimidinium chloride; 81461-72-5; 8-Pyrimidin-2-yl-5,8-diazaspiro[4.5]decan-5-ium chloride
EINECS	Contact for details

Quality Control

Our 8-(Pyrimidin-2-Yl)-5,8-Diazaspiro[4.5]Decan-5-Ium Chloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and supporting cGMP (current Good Manufacturing Practice) standards for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) in the original packaging to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.