Description

2-Methyl-6-Nitro-Imidazo[1,2-A]Pyridine-3-Carboxylic Acid Ethyl Ester is a high-value, nitrogen-containing heterocyclic building block with significant synthetic utility. This compound is primarily valued for its role as a key intermediate in the research and development of novel pharmaceutical agents, particularly in the creation of complex molecular scaffolds. It is essential for medicinal chemistry researchers and process development chemists working in the pharmaceutical, agrochemical, and advanced material sectors who require reliable, high-purity intermediates for their synthesis pipelines.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of potential drug candidates, especially those targeting infectious diseases or central nervous system disorders.
• Medicinal Chemistry Research: Used extensively in lead optimization and structure-activity relationship (SAR) studies to develop new bioactive molecules.
• Agrochemical Development: Acts as a building block for creating novel pesticides or herbicides with specific modes of action.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target identification.
• Advanced Material Synthesis: Potential use in constructing organic electronic materials or ligands for catalytic systems due to its fused heterocyclic structure.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up services for the life sciences industry.

Basic Information

Product Name	2-Methyl-6-Nitro-Imidazo[1,2-A]Pyridine-3-Carboxylic Acid Ethyl Ester
CAS No.	81438-60-0
Molecular Formula	C11H11N3O4
Molecular Weight	249.23 g/mol
Synonyms	Ethyl 2-Methyl-6-nitroimidazo[1,2-a]pyridine-3-carboxylate; 2-Methyl-6-nitroimidazo[1,2-a]pyridine-3-carboxylic acid ethyl ester; Imidazo[1,2-a]pyridine-3-carboxylic acid, 2-methyl-6-nitro-, ethyl ester; 81438-60-0; Ethyl 2-methyl-6-nitroimidazo[1,2-a]pyridine-3-carboxylate; 6-Nitro-2-methylimidazo[1,2-a]pyridine-3-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our 2-Methyl-6-Nitro-Imidazo[1,2-A]Pyridine-3-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.