Description

Pyridine, 3-Ethoxy-2-(Trimethylsilyl)- (9Ci) is a specialized organosilicon-substituted pyridine derivative, a key building block in advanced organic synthesis. This compound matters for its unique reactivity profile, combining the aromatic nitrogen base of pyridine with the protective and modifying properties of the trimethylsilyl and ethoxy groups. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those requiring silyl-protected heterocyclic systems.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the modified pyridine core imparts specific biological activity.
• Ligand and Catalyst Development: Acts as a starting material for creating sophisticated ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and other functional materials due to its electron-donating and steric properties.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions, nucleophilic substitutions, and as a directing group in metalation reactions.
• Chemical Research & Development: A valuable tool for methodological studies and exploring new reaction pathways in academic and industrial laboratories.

Basic Information

Item	Detail
Product Name	Pyridine, 3-Ethoxy-2-(Trimethylsilyl)- (9Ci)
CAS No.	81376-79-6
Molecular Formula	C12H21NOSi
Molecular Weight	223.39 g/mol
Synonyms	2-(Trimethylsilyl)-3-ethoxypyridine; 3-Ethoxy-2-(trimethylsilyl)pyridine; 3-Ethoxy-2-trimethylsilylpyridine; 2-Trimethylsilyl-3-ethoxypyridine; Pyridine, 3-ethoxy-2-(trimethylsilyl)-; (3-Ethoxypyridin-2-yl)trimethylsilane
EINECS	Contact for details

Quality Control

Our Pyridine, 3-Ethoxy-2-(Trimethylsilyl)- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and FTIR, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.