Description

(4R,5R)-2,2-Dimethyl-1,3-Dioxolane-4,5-Dicarboxylic Acid 4,5-Bis(1-Methylethyl) Ester is a high-purity chiral building block and protected derivative of tartaric acid. This compound is valued for its role in asymmetric synthesis, serving as a key precursor for catalysts, ligands, and complex pharmaceutical intermediates. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for developing enantiomerically pure products.

Application

• Asymmetric Synthesis: A crucial chiral auxiliary or starting material for the preparation of enantioselective catalysts and ligands.
• Pharmaceutical Intermediates: Used in the synthesis of active pharmaceutical ingredients (APIs) requiring high stereochemical purity.
• Agrochemical Development: Serves as a building block for chiral pesticides and herbicides.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances.
• Academic & Industrial Research: A standard reagent for methodological development in organic and medicinal chemistry.
• Ligand Synthesis: Precursor for tartrate-derived ligands used in metal-catalyzed reactions.

Basic Information

Product Name	(4R,5R)-2,2-Dimethyl-1,3-Dioxolane-4,5-Dicarboxylic Acid 4,5-Bis(1-Methylethyl) Ester
CAS No.	81327-47-1
Molecular Formula	C14H24O6
Molecular Weight	288.34 g/mol
Synonyms	(4R,5R)-Diisopropyl 2,2-Dimethyl-1,3-dioxolane-4,5-dicarboxylate; Diisopropyl (R,R)-2,2-Dimethyl-1,3-dioxolane-4,5-dicarboxylate; (R,R)-Diisopropyl Tartrate Acetonide; (4R,5R)-4,5-Bis(isopropoxycarbonyl)-2,2-dimethyl-1,3-dioxolane; L-(+)-Diisopropyl Tartrate Acetonide; DIPT Acetonide; (R,R)-DIPT Acetonide
EINECS	Contact for details

Quality Control

Our (4R,5R)-2,2-Dimethyl-1,3-Dioxolane-4,5-Dicarboxylic Acid 4,5-Bis(1-Methylethyl) Ester is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with exacting standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and enantiomeric excess is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Specific Rotation [α]20/D	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.