Description

Methyl 2-(3-Bromophenyl)-2-Oxoacetate is a high-purity organic building block and key synthetic intermediate. This compound is valued for its reactive α-keto ester functionality and the versatility introduced by the bromophenyl substituent, enabling precise molecular construction. It is primarily sought by research and development chemists in the pharmaceutical and agrochemical sectors for the synthesis of complex molecules, including active pharmaceutical ingredients (APIs) and advanced crop protection agents.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the development of advanced herbicides and fungicides, leveraging the bromine atom for further functionalization.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Employed in the synthesis of organic electronic materials and photoactive compounds due to its conjugated carbonyl system.
• Custom Synthesis and Contract Manufacturing: A key reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.
• Academic and R&D Laboratories: Used in methodological studies and for exploring new organic reactions, such as cross-couplings and condensations.

Basic Information

Product Name	Methyl 2-(3-Bromophenyl)-2-Oxoacetate
CAS No.	81316-36-1
Molecular Formula	C9H7BrO3
Molecular Weight	243.06 g/mol
Synonyms	Methyl 3-Bromobenzoylformate; 3-Bromophenylglyoxylic Acid Methyl Ester; Methyl (3-Bromobenzoyl)formate; Methyl α-Oxo-3-bromobenzeneacetate; 2-Oxo-2-(3-bromophenyl)acetic Acid Methyl Ester; (3-Bromobenzoyl)formic Acid Methyl Ester; Methyl 2-Oxo-2-(3-bromophenyl)acetate
EINECS	Contact for details

Quality Control

Every batch of Methyl 2-(3-Bromophenyl)-2-Oxoacetate is produced and tested under a strict quality management system. Our products undergo rigorous quality testing, including HPLC, GC, and NMR analysis, to ensure compliance with industry standards and customer specifications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.