Description

3,5-Pyridinedicarbonitrile, 4-Amino-2-Methyl- is a high-value heterocyclic building block featuring a pyridine core with strategically positioned amino and nitrile functional groups. This compound is critical for the synthesis of complex molecules, enabling the development of advanced materials and active pharmaceutical ingredients (APIs). It is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting kinase inhibition or other protein-protein interactions.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Ligand and Catalyst Development: The amino and nitrile groups make it a valuable starting material for creating chelating ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of organic semiconductors, conductive polymers, and metal-organic frameworks (MOFs) due to its electron-deficient pyridine ring and functional handles.
• Chemical Biology Probes: Acts as a scaffold for designing molecular probes and inhibitors used to study enzymatic pathways and cellular processes.
• Custom Synthesis and Contract Manufacturing: A vital building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	3,5-Pyridinedicarbonitrile, 4-Amino-2-Methyl-
CAS No.	81305-87-5
Molecular Formula	C8H6N4
Molecular Weight	158.16 g/mol
Synonyms	4-Amino-2-methylpyridine-3,5-dicarbonitrile; 2-Methyl-4-aminopyridine-3,5-dicarbonitrile; 4-Amino-2-methyl-3,5-pyridinedicarbonitrile; 3,5-Dicyano-4-amino-2-methylpyridine; 4-Amino-2-methyl-3,5-dicyanopyridine; 2-Methyl-4-amino-3,5-pyridinedicarbonitrile; 81305-87-5; 4-Amino-2-methylpyridine-3,5-dinitrile
EINECS	Contact for details

Quality Control

Our 3,5-Pyridinedicarbonitrile, 4-Amino-2-Methyl- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (IR, NMR), to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.