Description

4-Chloro-2,6-Bis(trifluoromethyl)pyridine is a high-value, multi-functional fluorinated pyridine derivative. This compound is prized for its unique chemical structure, which combines a halogenated pyridine core with electron-withdrawing trifluoromethyl groups, making it an essential advanced intermediate in modern synthetic chemistry. It is primarily utilized by R&D chemists and process engineers in the pharmaceutical and agrochemical sectors for constructing complex molecules.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring fluorinated motifs to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl groups enhance biological activity and environmental persistence.
• Ligand and Catalyst Precursor: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of fluorinated polymers, liquid crystals, and electronic materials for specialized applications.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	4-Chloro-2,6-Bis(trifluoromethyl)pyridine
CAS No.	81269-96-7
Molecular Formula	C7H2ClF6N
Molecular Weight	249.54 g/mol
Synonyms	2,6-Bis(trifluoromethyl)-4-chloropyridine; 4-Chloro-2,6-di(trifluoromethyl)pyridine; 4-Chloro-α,α,α,α',α',α'-hexafluoro-2,6-lutidine; Pyridine, 4-chloro-2,6-bis(trifluoromethyl)-
EINECS	Contact for details

Quality Control

We supply 4-Chloro-2,6-Bis(trifluoromethyl)pyridine in high-purity grades suitable for demanding R&D and scale-up applications. Our products undergo rigorous quality testing using advanced analytical techniques (HPLC, GC, NMR) to ensure batch-to-batch consistency and compliance with client specifications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.