Description

[3As-(3A,4,5,6A)]-(9Ci)-5-(Benzoyloxy)-4-[[[(1,1-Dimethylethyl)Dimethylsilyl]Oxy]Methyl]Hexahydro-2(1H)-Pentalenone is a sophisticated, high-purity organic intermediate featuring a protected hydroxyl group, making it a critical building block for advanced synthetic chemistry. Its precise molecular architecture is essential for constructing complex, biologically active molecules where regioselectivity and functional group compatibility are paramount. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of complex active pharmaceutical ingredients (APIs), particularly in steroid and terpenoid-related research.
• Organic Synthesis Building Block: Used in advanced organic reactions, including cross-coupling and asymmetric synthesis, to introduce specific functional groups into complex molecular frameworks.
• Medicinal Chemistry Research: Serves as a precursor for creating focused compound libraries to explore structure-activity relationships (SAR) in drug discovery programs.
• Process Chemistry Development: Employed in route scouting and optimization for the scalable production of high-value fine chemicals and candidate drugs.
• Academic Research: Utilized in university and institutional labs for methodological studies in synthetic organic chemistry and catalysis.

Basic Information

Product Name	[3As-(3A,4,5,6A)]-(9Ci)-5-(Benzoyloxy)-4-[[[(1,1-Dimethylethyl)Dimethylsilyl]Oxy]Methyl]Hexahydro-2(1H)-Pentalenone
CAS No.	81266-62-8
Molecular Formula	C23H34O4Si
Molecular Weight	402.60 g/mol
Synonyms	5-(Benzoyloxy)-4-[[(tert-butyldimethylsilyl)oxy]methyl]hexahydro-2(1H)-pentalenone; tert-Butyldimethylsilyl Ether of 5-Benzoyloxy-4-(hydroxymethyl)hexahydro-2(1H)-pentalenone; TBDMS Protected Pentalenone Derivative; (3aR,4S,5R,6aS)-5-(Benzoyloxy)-4-(((tert-butyldimethylsilyl)oxy)methyl)hexahydro-2H-cyclopenta[b]furan-2-one (stereospecific); CAS 81266-62-8; Benzoyl TBDMS Pentalenone; Advanced Steroid-like Intermediate
EINECS	Contact for details

Quality Control

Every batch of this high-value intermediate is produced and tested under strict quality management systems to ensure exceptional purity and batch-to-batch consistency. Our quality control protocols are designed to meet the exacting standards of pharmaceutical R&D and process chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity (by HPLC), and impurity profile is provided with each shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. This compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.