Description

1,4-o-Didesmethyl Rac-Niranthin is a high-purity synthetic intermediate and reference standard of significant interest in pharmaceutical research and development. This compound is valued for its role as a key building block in the synthesis of complex molecules and for its utility in analytical method development and validation. It is primarily sought after by research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in drug discovery, process chemistry, and quality control laboratories. Its availability as a well-characterized material supports critical work in medicinal chemistry and regulatory submissions.

Application

• Pharmaceutical Intermediate: Serves as a crucial synthetic precursor in the development of novel active pharmaceutical ingredients (APIs) and drug candidates.
• Analytical Reference Standard: Used for the identification, purity assessment, and quantification of related substances in research and quality control settings via HPLC, LC-MS, or NMR.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and the exploration of new therapeutic agents within academic and industrial R&D.
• Process Development & Scale-up: Acts as a benchmark material for optimizing synthetic routes and scaling production processes in fine chemical manufacturing.
• Metabolite Studies: Utilized in pharmacokinetic and metabolic pathway research to understand drug disposition and biotransformation.

Basic Information

Product Name	1,4-o-Didesmethyl Rac-Niranthin
CAS No.	81263-83-4
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Rac-Niranthin 1,4-o-Didesmethyl; Niranthin Derivative; 1,4-Didesmethylniranthin (racemic); (rac)-1,4-o-Didesmethylniranthin; 4-O-Demethylniranthin (racemic); Lignan derivative 81263-83-4; Research compound 81263-83-4
EINECS	Contact for details

Quality Control

Our 1,4-o-Didesmethyl Rac-Niranthin is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chromatographic purity assays and structural confirmation, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing identity, purity, and related substances is provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.