Description

(3Ar,4S,5R,6As)-5-Benzyloxy-4-Hydroxymethyl-Hexahydro-Cyclopenta[B]Furan-2-One CAS NO 81190-06-9 is a high-purity, stereochemically defined chiral building block and advanced pharmaceutical intermediate. This compound is critical for the synthesis of complex bioactive molecules, offering precise control over stereochemistry for researchers and manufacturers. It is primarily utilized in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals within the pharmaceutical, agrochemical, and advanced material sectors.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and commercial synthesis of proprietary drug candidates and complex APIs.
• Asymmetric Synthesis: Serves as a versatile starting material or intermediate for constructing stereocenters in total synthesis projects.
• Agrochemical Research: Used in the development of novel, stereospecific pesticides and herbicides where biological activity is enantiomer-dependent.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals requiring high stereochemical purity.
• Academic & R&D: A valuable reagent for methodological development in organic chemistry and medicinal chemistry research laboratories.
• Process Chemistry: Investigated for scale-up in GMP or non-GMP environments for the production of target molecules.

Basic Information

Product Name	(3Ar,4S,5R,6As)-5-Benzyloxy-4-Hydroxymethyl-Hexahydro-Cyclopenta[B]Furan-2-One
CAS No.	81190-06-9
Molecular Formula	C15H18O4
Molecular Weight	262.30 g/mol
Synonyms	5-Benzyloxy-4-(hydroxymethyl)hexahydrocyclopenta[b]furan-2-one; (3aR,4S,5R,6aS)-5-(Benzyloxy)-4-(hydroxymethyl)hexahydrocyclopenta[b]furan-2-one; Hexahydrocyclopenta[b]furan-2-one, 5-(benzyloxy)-4-(hydroxymethyl)-, (3aR,4S,5R,6aS)-; CAS 81190-06-9; Chiral Cyclopentafuranone Derivative; Benzyl-Protected Furanone Intermediate.
EINECS	Contact for details

Quality Control

Our production of (3Ar,4S,5R,6As)-5-Benzyloxy-4-Hydroxymethyl-Hexahydro-Cyclopenta[B]Furan-2-One adheres to stringent internal quality standards to ensure batch-to-batch consistency, high chiral purity, and chemical integrity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing key parameters such as assay, enantiomeric excess, and impurity profile. We are committed to meeting the exacting requirements of pharmaceutical R&D and cGMP manufacturing environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.