Description

4-(Bromomethyl)-2,6-Di-tert-Butylpyridine is a specialized brominated pyridine derivative that serves as a valuable synthetic intermediate and ligand precursor in advanced organic synthesis. Its sterically hindered structure and reactive bromomethyl group make it a critical building block for constructing complex molecules and functional materials. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for catalyst development and the synthesis of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs), particularly for creating sterically demanding ligands and complex heterocycles.
• Catalyst & Ligand Synthesis: Used to prepare sophisticated pyridine-based ligands for transition metal catalysis, enabling challenging cross-coupling and asymmetric transformations.
• Agrochemical Research: Intermediate in the development of new crop protection agents and herbicides, where its structural motif can impart stability and bioactivity.
• Material Science: Precursor for functionalized polymers and advanced organic materials, including metal-organic frameworks (MOFs) and liquid crystals.
• Chemical Biology Probes: Employed in the synthesis of molecular probes and tags for studying biological systems and enzyme mechanisms.
• Academic & Industrial R&D: A versatile reagent for methodological development in organic synthesis and process chemistry within research laboratories.

Basic Information

Product Name	4-(Bromomethyl)-2,6-Di-tert-Butylpyridine
CAS No.	81142-32-7
Molecular Formula	C15H24BrN
Molecular Weight	298.26 g/mol
Synonyms	2,6-Di-tert-butyl-4-(bromomethyl)pyridine; 4-(Bromomethyl)-2,6-bis(1,1-dimethylethyl)pyridine; 2,6-Di-tert-butyl-4-pyridinemethanol, bromide; 4-Bromomethyl-2,6-di-tert-butylpyridine; DTBP-Br; 2,6-DTBP-Br; 4-(Bromomethyl)-2,6-di-t-butylpyridine
EINECS	Contact for details

Quality Control

Our 4-(Bromomethyl)-2,6-Di-tert-Butylpyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.