Description

(E)-Methyl 3-(Pyridin-2-Yl)Acrylate CAS NO 81124-45-0 is a high-purity, versatile chemical intermediate featuring a conjugated ester system linked to a pyridine ring. This molecular architecture makes it a critical building block for synthesizing complex molecules in advanced research and industrial applications. It is primarily sought after by pharmaceutical R&D teams, agrochemical manufacturers, and specialty chemical producers for constructing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system or possessing anti-inflammatory properties.
• Agrochemical Synthesis: Serves as a building block for developing novel herbicides, fungicides, and plant growth regulators due to its bioactive pyridine-acrylate scaffold.
• Ligand and Catalyst Development: Used in organometallic chemistry to create chelating ligands for transition metal catalysts used in cross-coupling and other organic transformations.
• Material Science Research: Employed in the development of organic semiconductors, photoactive polymers, and advanced organic frameworks (MOFs/COFs).
• Fine Chemical Production: Intermediate for manufacturing dyes, pigments, and other specialty chemicals requiring a conjugated π-system.

Basic Information

Product Name	(E)-Methyl 3-(Pyridin-2-Yl)Acrylate
CAS No.	81124-45-0
Molecular Formula	C9H9NO2
Molecular Weight	163.17 g/mol
Synonyms	Methyl (E)-3-(2-Pyridyl)acrylate; (E)-Methyl 3-(2-Pyridinyl)-2-propenoate; trans-Methyl 3-(2-pyridyl)acrylate; 2-Propenoic acid, 3-(2-pyridinyl)-, methyl ester, (E)-; Methyl trans-3-(2-pyridyl)acrylate; 3-(Pyridin-2-yl)acrylic acid methyl ester
EINECS	Contact for details

Quality Control

Our (E)-Methyl 3-(Pyridin-2-Yl)Acrylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity (typically ≥97% by HPLC), residual solvents, and other critical parameters is provided with each shipment to guarantee it meets your precise research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is light-sensitive and should be handled under an inert atmosphere for prolonged stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.