Description

Isovaline, 4-Cyano-, Methyl Ester (9Ci) is a specialized organic compound belonging to the class of amino acid derivatives. This high-purity building block is critical for advanced research and development in pharmaceutical chemistry, particularly in the synthesis of novel peptide mimetics and bioactive molecules. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), especially for neurological and metabolic targets.
• Peptidomimetic Research: Used to synthesize non-natural amino acid analogs for creating stable peptide mimics with enhanced bioavailability and metabolic stability.
• Agrochemical Synthesis: Serves as a precursor in the development of novel herbicides and plant growth regulators with specific modes of action.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Bioconjugation Chemistry: Useful for introducing cyano and ester functional groups into biomolecules for labeling and probe development.
• Academic & Institutional Research: A valuable tool for methodological studies in organic synthesis and medicinal chemistry at universities and research institutes.

Basic Information

Product Name	Isovaline, 4-Cyano-, Methyl Ester (9Ci)
CAS No.	81080-74-2
Molecular Formula	C7H10N2O2
Molecular Weight	154.17 g/mol
Synonyms	Methyl 2-amino-2-methyl-4-cyanobutanoate; Methyl 4-cyanoisovaline; 2-Amino-2-methyl-4-cyanobutanoic acid methyl ester; 4-Cyanoisovaline methyl ester; (RS)-2-Amino-2-methyl-4-cyanobutanoic acid methyl ester; DL-4-Cyanoisovaline methyl ester; 2-Methyl-2-aminosuccinonitrile methyl ester
EINECS	Contact for details

Quality Control

Every batch of Isovaline, 4-Cyano-, Methyl Ester (9Ci) is manufactured under a strict quality management system. We provide comprehensive analytical documentation to ensure traceability and consistency for your critical R&D and scale-up processes. Certificates of Analysis (COA) detailing purity, chiral purity (if applicable), and impurity profiles by HPLC, GC, and NMR are available upon request and with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which may affect stability and handling properties. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.