Description

3-(4-tert-Butyl-Benzyloxy)-Pyridin-2-Ylamine is a high-purity, specialized organic intermediate featuring a pyridine core substituted with a tert-butyl benzyloxy group. This compound matters for its role as a critical building block in the synthesis of advanced pharmaceutical and agrochemical active ingredients. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop new molecules with enhanced properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Synthesis: Serves as a building block for developing new generation herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Ligand & Catalyst Development: Used in the research and preparation of specialized ligands for metal-catalyzed cross-coupling reactions and other catalytic processes.
• Material Science Research: Employed in the development of organic electronic materials, such as charge-transport layers or light-emitting components.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects and scale-up campaigns.

Basic Information

Product Name	3-(4-tert-Butyl-Benzyloxy)-Pyridin-2-Ylamine
CAS No.	81066-61-7
Molecular Formula	C₁₆H₂₀N₂O
Molecular Weight	256.34 g/mol
Synonyms	2-Amino-3-[(4-tert-butylphenyl)methoxy]pyridine; 3-[(4-tert-Butylbenzyl)oxy]pyridin-2-amine; 2-Pyridinamine, 3-[(4-(1,1-dimethylethyl)phenyl)methoxy]-; 3-(p-tert-Butylbenzyloxy)-2-aminopyridine; 3-(4-tert-Butyl-benzyloxy)-2-amino-pyridine; 81066-61-7; tert-Butylbenzyloxy pyridinamine derivative
EINECS	Contact for details

Quality Control

Our 3-(4-tert-Butyl-Benzyloxy)-Pyridin-2-Ylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets exacting standards for research and development use. Certificates of Analysis (COA) documenting batch-specific results are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is moisture-sensitive (hygroscopic); keep the original container tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.