Description

Chlorambucyl-Proline is a specialized chemical compound designed for advanced research and development applications. This high-purity intermediate is critical for synthetic chemists and pharmaceutical developers seeking to create novel molecular entities. It is primarily utilized in the life sciences sector, including pharmaceutical R&D and advanced material science, where precise chemical building blocks are essential. Its unique structure makes it a valuable asset for targeted synthesis projects.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs) and novel drug candidates.
• Protease Inhibitor Research: Used in biochemical research for studying enzyme mechanisms and developing protease inhibitors.
• Peptidomimetic Synthesis: Acts as a crucial component in the design and synthesis of peptidomimetics, which are molecules that mimic peptides.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to optimize the potency and selectivity of lead compounds.
• Bioconjugation: Utilized in the development of antibody-drug conjugates (ADCs) and other targeted therapeutic agents.
• Academic & Institutional Research: Supports fundamental chemical and biological research in university and institutional laboratories.

Basic Information

Product Name	Chlorambucyl-Proline
CAS No.	81050-71-7
Molecular Formula	C14H16ClN3O3
Molecular Weight	309.75 g/mol
Synonyms	L-Proline, 1-[(4-[[bis(2-chloroethyl)amino]phenyl]acetyl]-; N-[(4-[[Bis(2-chloroethyl)amino]phenyl]acetyl]-L-proline; Chlorambucil-Proline Conjugate; Chlorambucil-L-Proline; N-Chloroambucilyl-L-proline; 1-(p-[Bis(2-chloroethyl)amino]phenylacetyl)proline; (S)-1-(4-(Bis(2-chloroethyl)amino)phenylacetyl)pyrrolidine-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our Chlorambucyl-Proline is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity determination and spectroscopic methods for structural confirmation. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat and incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.