Description

Ethyl (S)-Pyrrolidine-3-Carboxylate is a high-purity chiral building block and key intermediate in organic synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs). It is essential for research and manufacturing in the pharmaceutical, agrochemical, and fine chemical industries, where precise stereochemistry is critical for product efficacy and regulatory approval.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of various drug candidates, including protease inhibitors, neurological agents, and other biologically active molecules.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides where specific stereoisomers are required for optimal activity.
• Asymmetric Catalysis: Serves as a precursor or ligand in the development of chiral catalysts for enantioselective synthesis.
• Fine Chemical Production: Employed in the custom synthesis of complex, high-value specialty chemicals for research and industrial applications.
• Academic & R&D: A valuable reagent in university and corporate research laboratories for methodological development and exploratory chemistry.

Basic Information

Product Name	Ethyl (S)-Pyrrolidine-3-Carboxylate
CAS No.	81049-27-6
Molecular Formula	C7H13NO2
Molecular Weight	143.18 g/mol
Synonyms	(S)-Ethyl Pyrrolidine-3-Carboxylate; (S)-1-Azabicyclo[3.1.0]hexane-3-carboxylic Acid Ethyl Ester; Ethyl (3S)-Pyrrolidine-3-Carboxylate; (S)-3-(Ethoxycarbonyl)pyrrolidine; L-Proline Ethyl Ester (related analog); Pyrrolidine-3-carboxylic Acid, Ethyl Ester, (S)-
EINECS	Contact for details

Quality Control

Our Ethyl (S)-Pyrrolidine-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for advanced synthetic applications. A Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere to maintain stability and purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.