Description

3-Carboxyumbelliferyl Acetate is a specialized fluorogenic substrate and a key chemical intermediate in the synthesis of diagnostic and research reagents. This compound is valued for its role in enzymatic assays, where its hydrolysis by specific esterases releases the highly fluorescent umbelliferone derivative, enabling sensitive detection and quantification. It is primarily needed by manufacturers and research institutions in the life sciences, pharmaceutical development, and clinical diagnostics sectors for developing high-throughput screening kits and biochemical probes.

Application

• Fluorogenic substrate for the detection and kinetic study of esterase and lipase enzymes.
• Key intermediate in the synthesis of advanced fluorescent probes and tags for bioimaging.
• Critical reagent in the development of diagnostic kits for clinical and veterinary use.
• Used in high-throughput screening (HTS) assays within pharmaceutical R&D for drug discovery.
• Component in environmental monitoring tests for detecting specific enzymatic activities.
• Research tool in biochemistry and molecular biology for studying enzyme mechanisms and inhibition.

Basic Information

Product Name	3-Carboxyumbelliferyl Acetate
CAS No.	81017-23-4
Molecular Formula	C12H8O6
Molecular Weight	248.19 g/mol
Synonyms	7-Acetoxy-3-carboxycoumarin; 3-Carboxy-7-acetoxycoumarin; 7-Acetoxycoumarin-3-carboxylic Acid; 3-Carboxyumbelliferyl 7-acetate; Umbelliferone-3-carboxylic Acid Acetate; 3-CUA; Fluorogenic Esterase Substrate
EINECS	Contact for details

Quality Control

Our 3-Carboxyumbelliferyl Acetate is produced under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for sensitive research and diagnostic applications. All products undergo rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a desiccated environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Fluorescence Properties	Conforms to reference

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.