Description

Boc-L-Glutamic Acid Dibenzyl Ester is a protected amino acid derivative of significant importance in synthetic organic and peptide chemistry. This compound serves as a crucial building block for the controlled synthesis of peptides and modified amino acids, offering orthogonal protection strategies. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors. The product is supplied under stringent quality control to ensure reliability for sensitive applications.

Application

• Peptide Synthesis: A key intermediate for the solid-phase and solution-phase synthesis of complex peptides, particularly those containing glutamic acid residues.
• Pharmaceutical Intermediates: Used in the research and development of novel active pharmaceutical ingredients (APIs) and prodrugs.
• Bioconjugation: Serves as a precursor for creating linkers and modified biomolecules used in antibody-drug conjugates (ADCs) and other bioconjugation strategies.
• Chemical Biology Probes: Employed in the synthesis of labeled amino acids and probes for studying enzyme mechanisms and protein interactions.
• Fine Chemical Production: Acts as a specialized intermediate in the manufacture of custom fine chemicals and advanced materials.
• Academic & Industrial R&D: Essential for research in medicinal chemistry, biochemistry, and material science laboratories worldwide.

Basic Information

Product Name	Boc-L-Glutamic Acid Dibenzyl Ester
CAS No.	80963-14-0
Molecular Formula	C24H29NO6
Molecular Weight	427.49 g/mol
Synonyms	N-(tert-Butoxycarbonyl)-L-glutamic acid dibenzyl ester; (2S)-2-[(tert-Butoxycarbonyl)amino]pentanedioic acid 1,5-dibenzyl ester; Boc-Glu(OBzl)-OBzl; Boc-L-Glu(OBzl)2; N-Boc-L-glutamic acid α,γ-dibenzyl ester; L-Glutamic acid, N-[(1,1-dimethylethoxy)carbonyl]-, 1,5-dibenzyl ester; Dibenzyl N-Boc-L-glutamate
EINECS	Contact for details

Quality Control

Our Boc-L-Glutamic Acid Dibenzyl Ester is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure high purity and consistency. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to strict quality management protocols to meet the exacting standards required for pharmaceutical research and fine chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation	Contact for details
Melting Point	Contact for details
Heavy Metals	<10 ppm
Residual Solvents	Complies with ICH guidelines
Water Content (KF)	<0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.