Description

L-Aspartic Acid, n-[(1,1-Dimethylethoxy)Carbonyl]-, 1-(1,1-Dimethylethyl) 4-(Phenylmethyl) Ester is a protected aspartic acid derivative, a crucial building block in modern organic synthesis. Its primary value lies in its role as a key intermediate for the controlled synthesis of peptides and peptidomimetics, enabling the development of pharmaceuticals and bioactive compounds. This high-purity intermediate is essential for research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require reliable, high-quality raw materials for advanced synthesis.

Application

• Pharmaceutical Intermediate: A critical building block in the solid-phase and solution-phase synthesis of peptide-based drugs and active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used to incorporate aspartic acid residues into peptide chains with orthogonal protecting groups (Boc and Bn) for selective deprotection.
• Bioconjugation & Labeling: Serves as a precursor for creating modified amino acids used in bioconjugation strategies for drug delivery systems or diagnostic agents.
• Research & Development: A valuable reagent in academic and industrial R&D for exploring new synthetic methodologies and developing novel bioactive molecules.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex organic molecules requiring protected amino acid functionalities.

Basic Information

Product Name	L-Aspartic Acid, n-[(1,1-Dimethylethoxy)Carbonyl]-, 1-(1,1-Dimethyl) 4-(Phenylmethyl) Ester
CAS No.	80963-08-2
Molecular Formula	C19H27NO6
Molecular Weight	365.42 g/mol
Synonyms	H-Asp(OtBu)-OBzl; L-Aspartic acid β-benzyl ester N-Boc derivative; Boc-Asp(OtBu)-OBzl; Boc-L-Aspartic acid 4-benzyl ester 1-tert-butyl ester; N-(tert-Butoxycarbonyl)-L-aspartic acid 1-tert-butyl 4-benzyl ester; (2S)-4-Benzyloxy-2-[(2-methylpropan-2-yl)oxycarbonylamino]-4-oxobutanoic acid tert-butyl ester; Boc-Asp(OtBu)-OBn; N-Boc-L-aspartic acid β-tert-butyl α-benzyl ester
EINECS	Contact for details

Quality Control

Our L-Aspartic Acid, n-[(1,1-Dimethylethoxy)Carbonyl]-, 1-(1,1-Dimethylethyl) 4-(Phenylmethyl) Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the high standards required for pharmaceutical intermediate applications. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation [α]	Contact for details
Chiral Purity (HPLC)	≥99.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.