Description

[2R,5S,(-)]-4,4'Aα,5,5',6',7',8',8'A-Octahydro-4'β-Hydroxy-2',5,5',5',8'Aβ-Pentamethylspiro[Furan-2(3H),1'(4'H)-Naphthalene]-5β-Acetic Acid is a complex, high-purity spirocyclic compound of significant interest in advanced organic synthesis. Its intricate stereochemistry and functional groups make it a valuable chiral building block and key intermediate for research and development. This compound is primarily sought by pharmaceutical, agrochemical, and specialty chemical manufacturers for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral synthon in the research and synthesis of novel drug candidates, particularly in areas requiring complex stereochemical control.
• Agrochemical Synthesis: Used as a building block in the development of advanced pesticides and herbicides with specific biological activity.
• Fine Chemical Production: Acts as a precursor in the manufacture of specialty chemicals, flavors, and fragrances where its unique spiro structure is advantageous.
• Academic & Industrial Research: Employed in methodological studies and as a reference standard in stereochemistry and total synthesis projects.
• Material Science: Potential application as a monomer or additive in the synthesis of specialized polymers with tailored properties.

Basic Information

Item	Details
Product Name	[2R,5S,(-)]-4,4'Aα,5,5',6',7',8',8'A-Octahydro-4'β-Hydroxy-2',5,5',5',8'Aβ-Pentamethylspiro[Furan-2(3H),1'(4'H)-Naphthalene]-5β-Acetic Acid
CAS No.	80952-79-0
Molecular Formula	C24H36O4
Molecular Weight	388.54 g/mol
Synonyms	(-)-Spiro[Furan-2(3H),1'(4'H)-Naphthalene]acetic acid derivative; 5β-Acetic acid, 4,4'a,5,5',6',7',8',8'a-octahydro-4'-hydroxy-2',5,5',5',8'aβ-pentamethylspiro[furan-2(3H),1'(4'H)-naphthalene]-, (2R,5S,4'β)-; Spirocyclic furan-naphthalene acetic acid; Chiral spiro intermediate; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our [2R,5S,(-)]-4,4'Aα,5,5',6',7',8',8'A-Octahydro-4'β-Hydroxy-2',5,5',5',8'Aβ-Pentamethylspiro[Furan-2(3H),1'(4'H)-Naphthalene]-5β-Acetic Acid is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis, to ensure it meets the high standards required for research and synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. For long-term storage, we recommend maintaining the product at temperatures between 2°C and 8°C. The compound may be hygroscopic; therefore, containers should be kept sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.