Description

[2R,5S,(+)]-4,4'Aα,5,5',6',7',8',8'A-Octahydro-4'α-Hydroxy-2',5,5',5',8'Aβ-Pentamethylspiro[Furan-2(3H),1'(4'H)-Naphthalene]-5β-Acetic Acid is a high-purity, stereochemically defined spirocyclic compound with significant synthetic utility. This compound matters as a sophisticated chiral building block and intermediate for the synthesis of complex natural products and novel active pharmaceutical ingredients (APIs). It is primarily needed by research institutions and pharmaceutical companies engaged in advanced organic synthesis, medicinal chemistry, and process development.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of steroidal or terpenoid-based drug candidates.
• Medicinal Chemistry Research: Used as a scaffold for designing and synthesizing novel bioactive molecules with potential therapeutic applications.
• Asymmetric Synthesis: Employed as a starting material or intermediate in complex, stereoselective total synthesis projects.
• Process Chemistry Development: Utilized in the scale-up and optimization of synthetic routes for target molecules in pilot and commercial manufacturing.
• Reference Standard: Acts as an analytical standard for quality control and method development in pharmaceutical analysis.
• Academic Research: Used in university and institutional labs for studying reaction mechanisms, catalysis, and new synthetic methodologies.

Basic Information

Product Name	[2R,5S,(+)]-4,4'Aα,5,5',6',7',8',8'A-Octahydro-4'α-Hydroxy-2',5,5',5',8'Aβ-Pentamethylspiro[Furan-2(3H),1'(4'H)-Naphthalene]-5β-Acetic Acid
CAS No.	80931-19-7
Molecular Formula	C24H36O4
Molecular Weight	388.54 g/mol
Synonyms	(+)-Spiro[4,5]decane-6-acetic acid derivative; (2R,5S)-Pentamethylspiro[furan-2(3H),1'(4'H)-naphthalene]acetic acid; 5β-Acetic acid, 4,4'a,5,5',6',7',8',8'a-octahydro-4'-hydroxy-2',5,5',5',8'aβ-pentamethylspiro[furan-2(3H),1'(4'H)-naphthalene]-, (2R,5S)-; 80931-19-7; Spirocyclic furan-naphthalene acetic acid; Chiral spiro intermediate; CAS 80931-19-7
EINECS	Contact for details

Quality Control

Our [2R,5S,(+)]-4,4'Aα,5,5',6',7',8',8'A-Octahydro-4'α-Hydroxy-2',5,5',5',8'Aβ-Pentamethylspiro[Furan-2(3H),1'(4'H)-Naphthalene]-5β-Acetic Acid is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure identity, strength, and purity. Certificates of Analysis (COA) documenting all test results are provided and available upon request to support your regulatory and research needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 98.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.