Description

L-Idaric-1,4-Lactone is a specialized chiral building block and sugar derivative of significant interest in advanced organic synthesis. Its unique stereochemistry makes it a valuable precursor for the development of complex molecules, particularly in pharmaceutical research and fine chemical manufacturing. This compound is essential for researchers and process chemists working on carbohydrate-based drugs, enzyme inhibitors, and novel bioactive compounds.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of novel drug candidates, particularly those targeting carbohydrate-processing enzymes.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies related to sugar metabolism and conversion pathways.
• Fine Chemical Synthesis: Serves as a versatile starting material for the preparation of complex, stereodefined natural product analogs and specialty chemicals.
• Glycochemistry: Building block for the construction of complex oligosaccharides, glycoconjugates, and glycomimetics with specific biological activities.
• Asymmetric Catalysis: Potential use as a chiral ligand precursor or auxiliary in stereoselective synthesis.

Basic Information

Product Name	L-Idaric-1,4-Lactone
CAS No.	80876-59-1
Molecular Formula	C6H8O6
Molecular Weight	176.12 g/mol
Synonyms	L-Idaro-1,4-lactone; (3R,4S,5R)-3,4,5-Trihydroxyoxane-2,6-dione; 1,4-L-Idonolactone; L-Idonic acid 1,4-lactone; L-(-)-Idaro-1,4-lactone; L-Idono-1,4-lactone; Idaric acid 1,4-lactone (L-form)
EINECS	Contact for details

Quality Control

Our L-Idaric-1,4-Lactone is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is characterized by modern analytical techniques, including HPLC, NMR, and optical rotation measurement. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral purity is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Specific Optical Rotation	Contact for details
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.