Description

(+)-Dibenzoyl-D-Tartaric Acid Monohydrate CAS NO 80822-15-7 is a high-purity chiral resolving agent and a key intermediate in asymmetric synthesis. Its primary value lies in its ability to separate enantiomers of racemic mixtures, particularly amines and amino acids, which is critical for producing single-isomer pharmaceuticals. This compound is essential for research and production in the pharmaceutical, fine chemical, and agrochemical industries, where optical purity is paramount for efficacy and safety.

Application

• Chiral Resolution Agent: Widely used for the optical resolution of racemic bases, alkaloids, and pharmaceutical intermediates via diastereomeric salt formation.
• Asymmetric Synthesis: Serves as a chiral auxiliary or catalyst precursor in stereoselective organic reactions.
• Pharmaceutical Manufacturing: Critical in the production of enantiomerically pure active pharmaceutical ingredients (APIs) for drugs targeting the central nervous system, cardiovascular diseases, and more.
• Analytical Chemistry: Used as a chiral selector in chromatography (HPLC, TLC) for the analysis and purification of enantiomers.
• Fine Chemical Synthesis: Employed in the synthesis of complex natural products, flavors, and fragrances requiring specific stereochemistry.
• Academic & Industrial R&D: A standard reagent in laboratories for method development and studying chiral recognition processes.

Basic Information

Product Name	(+)-Dibenzoyl-D-Tartaric Acid Monohydrate
CAS No.	80822-15-7
Molecular Formula	C18H14O8 • H2O
Molecular Weight	358.31 g/mol (Anhydrous basis: 340.30)
Synonyms	(+)-O,O'-Dibenzoyl-D-tartaric Acid Monohydrate; (2R,3R)-(+)-Di(benzoyloxy)succinic Acid Monohydrate; D-DBTA Monohydrate; D-(-)-Dibenzoyltartaric Acid Monohydrate; Dibenzoyl-D-tartaric Acid; (R,R)-Dibenzoyltartaric Acid Monohydrate; D-(+)-Dibenzoyltartaric Acid Monohydrate; Benzoyl-D-tartaric Acid
EINECS	Contact for details

Quality Control

Our (+)-Dibenzoyl-D-Tartaric Acid Monohydrate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical and optical purity, meeting the stringent requirements for chiral resolution and pharmaceutical synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity (HPLC/Chiral HPLC), optical rotation, and residual solvent levels is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed after opening to minimize exposure to atmospheric moisture and light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation [α]20/D	+120° to +130° (c=1 in ethanol)
Water Content (KF)	4.5% - 6.0% (Theoretical for monohydrate: ~5.0%)
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines
Chiral Purity (Chiral HPLC)	≥ 99.0% ee

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.