Description

Toluene-4-Sulfonic Acid Dimethoxy-Phosphorylmethyl Ester is a specialized organophosphorus compound that serves as a valuable synthetic intermediate and reagent in advanced chemical synthesis. Its unique structure, featuring both sulfonate and phosphonate ester functionalities, makes it a versatile building block for constructing complex molecules. This high-purity chemical is essential for research and production in the pharmaceutical, agrochemical, and specialty chemical industries, where precise molecular construction is critical.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring phosphonate or sulfonate ester linkages.
• Agrochemical Synthesis: Used in the production of advanced herbicides, insecticides, and plant growth regulators that incorporate organophosphorus chemistry.
• Ligand and Catalyst Precursor: Serves as a starting material for the preparation of specialized phosphonate-based ligands used in catalysis and metal complexation.
• Polymer Modification: Employed as a functional monomer or cross-linking agent to introduce specific ionic or reactive groups into polymer backbones.
• Peptide Synthesis & Modification: Useful in peptide chemistry for the selective protection or activation of functional groups.
• Material Science Research: Applied in the development of novel materials, including flame retardants, surfactants, and ionic liquids.
• Chemical Biology Probes: Acts as a precursor for synthesizing probes and inhibitors that target enzymes like phosphatases and kinases.

Basic Information

Item	Details
Product Name	Toluene-4-Sulfonic Acid Dimethoxy-Phosphorylmethyl Ester
CAS No.	80792-13-8
Molecular Formula	C10H15O6PS
Molecular Weight	294.26 g/mol
Synonyms	p-Toluenesulfonic Acid (Dimethoxyphosphoryl)methyl Ester; (Dimethoxyphosphoryl)methyl p-Toluenesulfonate; Phosphonic acid, P-[(p-tolylsulfonyl)methyl]-, dimethyl ester; Tosyloxymethyldimethyl Phosphonate; Dimethyl (p-Toluenesulfonyloxymethyl)phosphonate; Dimethyl [(4-methylphenyl)sulfonyloxy]methylphosphonate; 80792-13-8; (Tosyloxy)methyldimethylphosphonate
EINECS	Contact for details

Quality Control

Our Toluene-4-Sulfonic Acid Dimethoxy-Phosphorylmethyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chromatography and spectroscopy, to ensure high purity and consistent performance. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profiles is provided with every shipment to guarantee it meets your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials. The container should be kept tightly sealed in a dry environment to minimize moisture exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.