Description

5-Aminotetramethylrhodamine is a high-purity, fluorescent dye derivative of the widely used rhodamine family. This compound is valued for its excellent photostability and bright fluorescence, making it a critical component in advanced labeling and detection technologies. It is primarily utilized by researchers and manufacturers in the life sciences, diagnostics, and analytical chemistry sectors for applications requiring sensitive and specific molecular tagging.

Application

• Fluorescent Labeling Agent: Used for covalent conjugation to proteins, antibodies, oligonucleotides, and other biomolecules for fluorescence microscopy, flow cytometry, and immunoassays.
• Bioconjugation & Probe Synthesis: A key reactive intermediate in the synthesis of fluorescent probes, sensors, and molecular beacons for real-time biological imaging and detection.
• Diagnostic Reagent Manufacturing: Incorporated into diagnostic kits and assays for clinical testing, pathogen detection, and genetic analysis.
• Cell & Tissue Staining: Employed in histological and cytological studies to visualize specific cellular structures or track biological processes.
• Material Science Research: Used in the development of photonic materials, sensors, and light-harvesting systems due to its favorable photophysical properties.

Basic Information

Product Name	5-Aminotetramethylrhodamine
CAS No.	80724-17-0
Molecular Formula	C25H23N3O3
Molecular Weight	413.47 g/mol
Synonyms	5-Amino TAMRA; 5-TAMRA amine; 5-Carboxytetramethylrhodamine amine; 6-Amino-3',6'-diaminospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one; 5-Isomer of TAMRA amine; Rhodamine B 5-isomer amine; 5-(and-6)-TAMRA, SE isomer; 5/6-TAMRA amine mixture (5-isomer specified)
EINECS	Contact for details

Quality Control

Our 5-Aminotetramethylrhodamine is produced under strict quality management systems to ensure batch-to-batch consistency and high performance. Each lot undergoes comprehensive analytical testing, including HPLC for purity, spectroscopic analysis for identity confirmation, and functional testing for labeling efficiency. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key specifications such as purity, absorbance/fluorescence profiles, and moisture content.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is light-sensitive (store away from light) and should be handled under appropriate conditions to prevent degradation. For long-term storage, consider storing desiccated at -20°C.

Specification

Item	Specification
Appearance	Dark red to purple powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95% (typical ≥ 98%)
Absorption Max (λmax)	~540-560 nm
Emission Max	~565-585 nm
Extinction Coefficient (ε)	Contact for details
Fluorescence Quantum Yield	Contact for details
Loss on Drying	≤ 2.0 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.