Description

3-Cyclopentene-1,2-Diol, 5-(Hydroxymethyl)-, 1,2-Dibenzoate, 1R-(1.Alpha.,2.Beta.,5.Beta.)- is a high-purity, stereochemically defined chiral building block of significant interest in advanced organic synthesis. Its complex, functionalized cyclopentene core makes it a valuable precursor for the development of novel pharmaceuticals and fine chemicals. This compound is primarily sought by research institutions and industrial R&D departments focused on asymmetric synthesis, medicinal chemistry, and the production of complex bioactive molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex stereochemistry.
• Asymmetric Synthesis: Serves as a sophisticated starting material or intermediate in catalytic asymmetric reactions to construct molecules with high enantiomeric purity.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to explore novel chemical spaces for drug discovery.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals, flavors, fragrances, and advanced materials where precise stereocontrol is essential.
• Academic & Industrial R&D: A valuable tool for methodological development in organic chemistry and for creating libraries of complex molecules for screening.

Basic Information

Product Name	3-Cyclopentene-1,2-Diol, 5-(Hydroxymethyl)-, 1,2-Dibenzoate, 1R-(1.Alpha.,2.Beta.,5.Beta.)-
CAS No.	80675-64-5
Molecular Formula	C20H18O5
Molecular Weight	338.35 g/mol
Synonyms	(1R,2R,5R)-5-(Hydroxymethyl)cyclopent-3-ene-1,2-diyl dibenzoate; (1R,2R,5R)-5-(Hydroxymethyl)-3-cyclopentene-1,2-diol 1,2-Dibenzoate; 1R-(1α,2β,5β)-5-(Hydroxymethyl)cyclopent-3-ene-1,2-diyl dibenzoate; Chiral Cyclopentene Dibenzoate Derivative; (1R,2R,5R)-3-Cyclopentene-1,2-diol, 5-(hydroxymethyl)-, 1,2-dibenzoate
EINECS	Contact for details

Quality Control

We supply this advanced intermediate under strict quality protocols suitable for research and development applications. Our standard grade typically features a purity of ≥97% (by HPLC), with enantiomeric excess (ee) specifications available upon request. All batches are supported by comprehensive Certificates of Analysis (COA) detailing identity, purity, and chiral purity. We adhere to cGMP principles where applicable and can accommodate custom purity or analytical requirements for specific project needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This compound is moisture-sensitive; keep the container tightly sealed in a dry environment. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥97.0%
Enantiomeric Excess (Chiral HPLC)	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.