Description

Cholecalciferol, also known as vitamin D3, is a vital secosteroid hormone essential for calcium and phosphate homeostasis in the body. Its primary commercial value lies in its critical role in nutritional fortification and pharmaceutical applications to prevent and treat deficiency-related disorders. This high-purity compound is indispensable for manufacturers in the pharmaceutical, nutraceutical, and food & beverage industries, where it is used in dietary supplements, infant formula, medical foods, and animal feed premixes.

Application

• Pharmaceutical Formulations: Active pharmaceutical ingredient (API) in prescription and over-the-counter medications for treating vitamin D deficiency, osteoporosis, and renal osteodystrophy.
• Dietary Supplements: Key ingredient in softgel capsules, tablets, and liquid multivitamin formulations for general wellness and bone health support.
• Food & Beverage Fortification: Used to fortify staple foods such as milk, dairy alternatives, breakfast cereals, and infant formula to address public health nutritional gaps.
• Animal Nutrition: Essential component in poultry, swine, and aquaculture feed premixes to ensure proper bone development, eggshell quality, and overall animal health.
• Cosmeceuticals: Incorporated into topical skincare products for its role in supporting skin cell metabolism and barrier function.
• Clinical Research: Serves as a reference standard and reagent in biochemical research and diagnostic assay development.

Basic Information

Item	Details
Product Name	Cholecalciferol
CAS No.	80666-48-4
Molecular Formula	C₂₇H₄₄O
Molecular Weight	384.64 g/mol
Synonyms	Vitamin D3; Colecalciferol; 7-Dehydrocholesterol activated; Activated 7-dehydrocholesterol; Calciol; Oleovitamin D3; 9,10-Secocholesta-5,7,10(19)-trien-3β-ol; (3β,5Z,7E)-9,10-Secocholesta-5,7,10(19)-trien-3-ol
EINECS	Contact for details

Quality Control

Our Cholecalciferol is manufactured under strict quality management systems. It is typically produced to meet or exceed relevant pharmacopeial standards such as USP, EP, and FCC specifications for identity, purity, and potency. Our products undergo rigorous quality testing, including advanced chromatographic assays, to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen) in a cool, dry place at 2-8°C (refrigerated) or as specified on the label. This product is strictly light-sensitive and easily oxidized; prolonged exposure to light, air, or elevated temperatures must be avoided to maintain stability and potency.

Specification

Item	Specification
Appearance	White to slightly yellow crystals or crystalline powder
Identification (IR)	Conforms to standard
Assay (HPLC)	≥ 98.0%
Specific Rotation	+105° to +112°
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.