Description

(2R,3R)-Diethyl 2-Bromo-3-Hydroxysuccinate is a high-purity chiral building block and synthetic intermediate of significant value in advanced organic synthesis. Its defined stereochemistry and functional groups make it a critical precursor for constructing complex molecules with precise three-dimensional architecture. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for the development of active pharmaceutical ingredients (APIs) and specialty agrochemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the asymmetric synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and production of enantiomerically pure pesticides and herbicides.
• Fine Chemical Production: Serves as a versatile building block for creating specialty chemicals, flavors, and fragrances.
• Academic & Industrial Research: A valuable reagent in methodological development for stereoselective synthesis and catalysis studies.
• Peptidomimetic & Natural Product Synthesis: Employed in the construction of peptide analogs and complex natural product scaffolds.

Basic Information

Product Name	(2R,3R)-Diethyl 2-Bromo-3-Hydroxysuccinate
CAS No.	80640-15-9
Molecular Formula	C8H13BrO5
Molecular Weight	269.09 g/mol
Synonyms	Diethyl (2R,3R)-2-Bromo-3-hydroxysuccinate; (2R,3R)-2-Bromo-3-hydroxybutanedioic Acid Diethyl Ester; L-(+)-Diethyl 2-Bromo-3-hydroxysuccinate; Diethyl (2R,3R)-2-Bromo-3-hydroxybutanedioate; 2-Bromo-3-hydroxysuccinic Acid Diethyl Ester (stereospecific); (2R,3R)-2-Bromo-3-hydroxy-succinic Acid Diethyl Ester
EINECS	Contact for details

Quality Control

Our (2R,3R)-Diethyl 2-Bromo-3-Hydroxysuccinate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure high enantiomeric excess (ee) and chemical purity. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency, meeting the stringent requirements of research and cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque or amber packaging.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.