Description

Diethyl (2S,3S)-2-Bromo-3-Hydroxysuccinate is a high-value chiral building block and synthetic intermediate of significant importance in advanced organic synthesis. Its defined stereochemistry and reactive functional groups make it a versatile precursor for constructing complex molecules with precise three-dimensional architecture. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for the development of active pharmaceutical ingredients (APIs), chiral ligands, and other specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the asymmetric synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and production of chiral pesticides and herbicides requiring specific stereochemistry for efficacy.
• Fine Chemical Production: Serves as a precursor for specialty chemicals, including chiral catalysts, ligands for asymmetric catalysis, and advanced materials.
• Academic & Industrial Research: A valuable reagent in methodological development for stereoselective synthesis, including aldol reactions and nucleophilic substitutions.
• Peptidomimetics & Bioactive Molecules: Employed in the construction of peptide analogs and other bioactive compounds with defined stereocenters.

Basic Information

Product Name	Diethyl (2S,3S)-2-Bromo-3-Hydroxysuccinate
CAS No.	80640-14-8
Molecular Formula	C8H13BrO5
Molecular Weight	269.09 g/mol
Synonyms	(2S,3S)-Diethyl 2-bromo-3-hydroxysuccinate; Diethyl (2S,3S)-2-bromo-3-hydroxybutanedioate; (2S,3S)-2-Bromo-3-hydroxysuccinic Acid Diethyl Ester; L-threo-Diethyl 2-bromo-3-hydroxysuccinate; Ethyl (2S,3S)-2-bromo-3-hydroxybutanedioate; 80640-14-8; (2S,3S)-2-Bromo-3-hydroxy-succinic acid diethyl ester
EINECS	Contact for details

Quality Control

Our Diethyl (2S,3S)-2-Bromo-3-Hydroxysuccinate is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.