Description

[[3-(Trimethylsilyl)Propyl]Thio]Acetic Acid Methyl Ester is a specialized organosilicon compound featuring a thioether linkage and an ester group, making it a versatile reagent for introducing functionalized silyl groups. This compound is valued for its role as a key intermediate in the synthesis of advanced materials and bioactive molecules, where its unique structure enables precise surface modification and controlled chemical derivatization. It is primarily sought by R&D chemists and process engineers in the pharmaceutical, agrochemical, and advanced polymer industries for applications requiring tailored silicon-based chemistry.

Application

• Silane Coupling Agent Precursor: Used to synthesize novel silane coupling agents for enhancing adhesion between inorganic fillers and organic polymer matrices in composites and sealants.
• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of drug candidates, particularly those requiring thioether or silicon-containing functional groups for improved bioavailability or metabolic stability.
• Surface Modification Reagent: Employed to functionalize silica, glass, or metal oxide surfaces, imparting specific chemical properties for chromatography, sensors, or nanotechnology applications.
• Polymer Additive Synthesis: Acts as an intermediate in creating specialized additives for polymers, such as stabilizers, cross-linking agents, or modifiers to alter surface energy.
• Agrochemical Intermediate: Utilized in the production of certain pesticides or herbicides where the silyl-thioether moiety contributes to the desired biological activity or environmental profile.
• Ligand Synthesis for Catalysis: A starting material for preparing sophisticated ligands used in transition metal catalysis for asymmetric synthesis.

Basic Information

Product Name	[[3-(Trimethylsilyl)Propyl]Thio]Acetic Acid Methyl Ester
CAS No.	80496-50-0
Molecular Formula	C9H20O2SSi
Molecular Weight	220.41 g/mol
Synonyms	Methyl 3-((Trimethylsilyl)thio)propanoate; Methyl [[3-(Trimethylsilyl)propyl]thio]acetate; 3-[(Trimethylsilyl)thio]propionic Acid Methyl Ester; (3-Mercaptopropyl)trimethylsilane Acetic Acid Methyl Ester; TMS-Thiopropionate Methyl Ester; 80496-50-0; Methyl 3-(trimethylsilylthio)propionate
EINECS	Contact for details

Quality Control

Our production of [[3-(Trimethylsilyl)Propyl]Thio]Acetic Acid Methyl Ester adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot is characterized using advanced analytical techniques including GC, HPLC, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment, supporting compliance with internal and regulatory standards for research and manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); containers must be kept tightly sealed to exclude moisture and prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.