Description

1-Phenyl-1-Propanone o-(Trimethylsilylmethyl)Oxime is a specialized organosilicon building block featuring a reactive oxime functional group. This compound is valued for its role as a versatile synthon in advanced organic synthesis, particularly in the construction of complex molecular architectures. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for creating novel silicon-containing intermediates.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially those incorporating silicon to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, where the trimethylsilyl group can act as a protective moiety or influence biological activity.
• Organometallic Chemistry: Serves as a precursor for generating metal complexes and catalysts used in cross-coupling and other transition metal-catalyzed reactions.
• Material Science Research: Employed in the development of specialty polymers, silicones, and advanced materials with tailored surface properties.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic synthesis, including the development of new C-C and C-N bond-forming reactions.

Basic Information

Product Name	1-Phenyl-1-Propanone o-(Trimethylsilylmethyl)Oxime
CAS No.	80496-48-6
Molecular Formula	C13H21NOSi
Molecular Weight	235.40 g/mol
Synonyms	Propiophenone, O-[(trimethylsilyl)methyl]oxime; 1-Phenyl-1-propanone O-[(trimethylsilyl)methyl]oxime; α-(Trimethylsilylmethyl)oxime of Propiophenone; (Trimethylsilyl)methyl propiophenone oxime; TMSM-Propiophenone oxime
EINECS	Contact for details

Quality Control

Our production of 1-Phenyl-1-Propanone o-(Trimethylsilylmethyl)Oxime adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and GC-MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.