Description

Niphithricin A CAS NO 80450-11-9 is a specialized natural product compound belonging to the class of polyketide macrolides. This compound is of significant interest for its potential biological activity, making it a valuable candidate for research and development in life sciences. It is primarily utilized by pharmaceutical research institutions, biotechnology companies, and academic laboratories engaged in drug discovery, antimicrobial studies, and chemical biology.

Application

• Pharmaceutical Research & Drug Discovery: Serves as a lead compound or reference standard in the development of novel therapeutic agents, particularly for investigating antimicrobial or antifungal pathways.
• Antimicrobial Activity Studies: Used in bioassays to evaluate efficacy against various bacterial and fungal strains, supporting the development of new antibiotics.
• Biochemical Research: Employed as a tool compound to study specific enzyme inhibition, cellular processes, and structure-activity relationships (SAR) of macrolide derivatives.
• Academic & Institutional Research: Provides a high-purity chemical entity for fundamental research in organic chemistry, natural product chemistry, and pharmacology.
• Reference Standard for Analytical Testing: Used in HPLC, LC-MS, or NMR for method development, validation, and quality control of related substances in research samples.

Basic Information

Product Name	Niphithricin A
CAS No.	80450-11-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Niphithricin A; Antibiotic Niphithricin A; 80450-11-9; (3E,5E,7E,9E,11E,13E,15E,17E,19E)-20-[(2R,3S,4S,5S,6R)-4-amino-3,5-dihydroxy-6-methyloxan-2-yl]oxy-3,5,9,11,15,17-hexamethyl-4,8,12,16-tetraoxo-2-oxacycloeicosa-3,5,7,9,11,13,15,17,19-nonaen-10-yl acetate (IUPAC); Niphitricin A
EINECS	Contact for details

Quality Control

Our Niphithricin A is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and reliability for research applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity and spectroscopic methods for identity confirmation. A Certificate of Analysis (COA) detailing specific test results is provided with every shipment to support your research integrity and documentation needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere. The product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (NMR)	Spectrum consistent with structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.