Description

5-Decyano 5-(Ethyl Formate) Milrinone is a key pharmaceutical intermediate and a derivative of the cardiotonic agent Milrinone. This compound matters for its critical role in the synthesis and research of cardiovascular drugs, particularly positive inotropic agents. It is primarily needed by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of Milrinone and related cardiotonic agents.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop novel cardiovascular therapeutics.
• Process Development & Scale-up: Serves as a reference standard and starting material for optimizing synthetic routes in API manufacturing.
• Biochemical Research: Employed in studies investigating phosphodiesterase (PDE3) inhibition mechanisms.
• Reference Standard: Used in analytical laboratories for method development, validation, and quality control testing.
• Custom Synthesis: A precursor for the preparation of novel Milrinone analogs and derivatives for patenting and screening.

Basic Information

Product Name	5-Decyano 5-(Ethyl Formate) Milrinone
CAS No.	80442-07-5
Molecular Formula	C15H15N3O3
Molecular Weight	285.30 g/mol
Synonyms	1,6-Dihydro-2-methyl-6-oxo-[3,4'-bipyridine]-5-carbonitrile, 5-(Ethoxycarbonyl); Milrinone Impurity; Milrinone Intermediate; 2-Methyl-5-cyano-1,6-dihydro-6-oxo-[3,4'-bipyridine]-5-carboxylic Acid Ethyl Ester; 5-Cyano-1,6-dihydro-2-methyl-6-oxo-3,4'-bipyridine-5-carboxylic Acid Ethyl Ester; Ethyl 5-Cyano-1,6-dihydro-2-methyl-6-oxo-3,4'-bipyridine-5-carboxylate
EINECS	Contact for details

Quality Control

Our 5-Decyano 5-(Ethyl Formate) Milrinone is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.