Description

4-(Acetylamino)Benzylphosphonate is a specialized organophosphorus compound featuring a benzylphosphonate core functionalized with an acetylamino group. This unique structure makes it a valuable intermediate in the synthesis of complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists working on novel active ingredients, enzyme inhibitors, and functional materials. The compound's phosphonate moiety offers versatile reactivity for constructing carbon-phosphorus bonds, which are critical in many bioactive compounds.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, especially those targeting bone diseases, viral infections, or acting as enzyme inhibitors.
• Agrochemical Research: Used in developing novel herbicides, plant growth regulators, or pesticides where the phosphonate group can mimic natural phosphates.
• Chemical Biology Probe: Serves as a precursor for activity-based probes or inhibitors to study phosphonate-metabolizing enzymes and biological pathways.
• Ligand Synthesis: Intermediate for creating chelating agents or ligands used in catalysis and metal ion sequestration.
• Material Science Precursor: Potential monomer or additive in the development of specialty polymers, flame retardants, or surface-modifying agents.
• Academic & Industrial R&D: Fundamental research chemical for exploring new synthetic methodologies and reaction mechanisms involving phosphonates.

Basic Information

Product Name	4-(Acetylamino)Benzylphosphonate
CAS No.	80434-81-7
Molecular Formula	C9H12NO4P
Molecular Weight	229.17 g/mol
Synonyms	4-Acetamidobenzylphosphonic Acid; N-[4-(Dihydroxyphosphinylmethyl)phenyl]acetamide; p-Acetamidobenzylphosphonic Acid; 4-(Acetylamino)benzylphosphonic Acid; Phosphonic acid, P-[4-(acetylamino)phenyl]methyl-; Acetamide, N-[4-(phosphonomethyl)phenyl]-; (4-Acetamidobenzyl)phosphonic Acid
EINECS	Contact for details

Quality Control

Our 4-(Acetylamino)Benzylphosphonate is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes data from techniques such as HPLC, NMR, and mass spectrometry. Our quality commitment ensures the material meets the stringent requirements for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept sealed when not in use to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.