Description

3-Bromo-2,6-Difluoropyridine is a high-purity halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring bromine and fluorine substituents at strategic positions, makes it an invaluable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is essential for R&D and production chemists in the pharmaceutical, agrochemical, and material science industries seeking to introduce halogenated pyridine motifs into their target compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and anti-infective agents.
• Agrochemical Synthesis: Used to develop novel herbicides, fungicides, and insecticides, where the difluoropyridine core enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Building block for organic electronic materials, such as semiconductors and light-emitting diodes (OLEDs), due to its electron-deficient aromatic system.
• Cross-Coupling Reactions: The bromine atom is an excellent handle for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Fluorine Chemistry Exploration: Used in studies to understand the influence of fluorine atoms on molecular conformation, lipophilicity, and binding affinity.

Basic Information

Product Name	3-Bromo-2,6-Difluoropyridine
CAS No.	80392-79-6
Molecular Formula	C5H2BrF2N
Molecular Weight	193.98 g/mol
Synonyms	2,6-Difluoro-3-bromopyridine; 3-Bromo-2,6-difluoropyridine; Pyridine, 3-bromo-2,6-difluoro-; 80392-79-6; 3-Br-2,6-F2-Py; 3-Bromo-2,6-difluoro-pyridine
EINECS	Contact for details

Quality Control

Our 3-Bromo-2,6-Difluoropyridine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and industry standards for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.