Description

Methyl 2'-Fluoro[1,1'-Biphenyl]-3-Carboxylate CAS NO 80254-83-7 is a high-purity fluorinated biphenyl ester derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in providing a versatile and functionalized aromatic scaffold essential for constructing complex molecular architectures. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and plant growth regulators, where the fluorine atom and biphenyl core enhance biological activity and stability.
• Liquid Crystal & OLED Material Precursor: Serves as a foundational unit for creating fluorinated aromatic compounds used in electronic display technologies and organic light-emitting diodes (OLEDs).
• Organic Synthesis & Catalysis Research: Employed in cross-coupling reactions (e.g., Suzuki, Stille) and as a ligand precursor in catalytic systems due to its steric and electronic properties.
• Fluorine Chemistry Studies: A valuable substrate for investigating the effects of fluorine substitution on reaction pathways and physicochemical properties in aromatic systems.

Basic Information

Item	Details
Product Name	Methyl 2'-Fluoro[1,1'-Biphenyl]-3-Carboxylate
CAS No.	80254-83-7
Molecular Formula	C14H11FO2
Molecular Weight	230.24 g/mol
Synonyms	Methyl 2'-Fluorobiphenyl-3-carboxylate; 2'-Fluoro-3-biphenylcarboxylic Acid Methyl Ester; 3-(2-Fluorophenyl)benzoic Acid Methyl Ester; Methyl 3-(2-Fluorophenyl)benzoate; 2'-Fluoro[1,1'-biphenyl]-3-carboxylic Acid Methyl Ester; 80254-83-7; Biphenyl-3-carboxylic acid, 2'-fluoro-, methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 2'-Fluoro[1,1'-Biphenyl]-3-Carboxylate is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.