Description

3-[3-(2-Chloroethyl)-3-Nitrosoureido]-3-Deoxy-α-D-Glucopyranose is a specialized nitrosourea derivative of a modified sugar, representing a key intermediate in advanced pharmaceutical research and development. This compound is valued for its role in the synthesis of targeted chemotherapeutic agents and other bioactive molecules, offering researchers a precise tool for structure-activity relationship studies. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and fine chemical manufacturers focused on oncology and medicinal chemistry.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel nitrosourea-based chemotherapeutic drugs and targeted cancer therapies.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop new bioactive compounds with potential antitumor activity.
• Bioconjugation & Prodrug Development: Serves as a linker or functional group for creating targeted drug conjugates and prodrugs designed for specific delivery.
• Biochemical Tool Compound: Employed in laboratory studies to investigate alkylating agent mechanisms and DNA interaction pathways.
• Fine Chemical Synthesis: Used as a specialized reagent in multi-step organic syntheses requiring a sugar-based nitrosourea moiety.
• Academic & Institutional Research: Supports fundamental research in chemical biology, oncology, and drug discovery programs at universities and research institutes.

Basic Information

Product Name	3-[3-(2-Chloroethyl)-3-Nitrosoureido]-3-Deoxy-α-D-Glucopyranose
CAS No.	80240-96-6
Molecular Formula	C9H15ClN4O7
Molecular Weight	326.69 g/mol
Synonyms	3-Deoxy-3-[3-(2-chloroethyl)-3-nitrosoureido]-α-D-glucopyranose; 1-(2-Chloroethyl)-3-(3-deoxy-α-D-glucopyranos-3-yl)-1-nitrosourea; Chlorozotocin analog; D-Glucose, 3-deoxy-3-[[[[(2-chloroethyl)nitrosoamino]carbonyl]amino]-; CCNU-Glucose Derivative; Nitrosourea-Glucose Conjugate; 3-(3-(2-Chloroethyl)-3-nitrosoureido)-3-deoxy-α-D-glucopyranose
EINECS	Contact for details

Quality Control

Our 3-[3-(2-Chloroethyl)-3-Nitrosoureido]-3-Deoxy-α-D-Glucopyranose is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 95.0%
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.