Description

Enterodiol is a mammalian lignan metabolite produced by the gut microbiota from dietary precursors. This compound is of significant interest for its role as a biomarker and its potential bioactive properties in human health and nutrition research. It is primarily utilized by research institutions, nutraceutical developers, and analytical laboratories focused on metabolomics, phytoestrogen studies, and gut health. Enterodiol CAS NO 80226-00-2 is a key standard for accurate quantification and metabolic pathway analysis.

Application

• Biomedical Research Standard: Used as a high-purity reference standard in LC-MS, GC-MS, and HPLC analyses for quantifying lignan metabolites in biological samples (plasma, urine, tissues).
• Nutraceutical & Functional Food Development: Serves as a marker compound for standardizing and validating the potency of flaxseed, sesame, and other lignan-rich dietary supplements.
• Metabolomics & Gut Microbiome Studies: Essential for investigating the metabolic conversion of plant lignans (e.g., secoisolariciresinol diglucoside) by intestinal bacteria and its subsequent bioavailability.
• Pharmacological Research: Employed in in vitro and in vivo studies to explore potential health benefits related to hormonal balance, antioxidant activity, and cardiometabolic health.
• Clinical Trial Support: Used to calibrate assays in intervention studies examining the impact of high-lignan diets on human health outcomes.
• Quality Control in Manufacturing: Acts as a critical purity standard for manufacturers producing lignan extracts or related botanical ingredients.

Basic Information

Product Name	Enterodiol
CAS No.	80226-00-2
Molecular Formula	C20H26O4
Molecular Weight	330.42 g/mol
Synonyms	2,3-Bis(3-hydroxybenzyl)butane-1,4-diol; (-)-Enterodiol; (2R,3R)-2,3-Bis[(3-hydroxyphenyl)methyl]butane-1,4-diol; END; Mammalian Lignan; HPMF Metabolite; Lignan Diol; Secoisolariciresinol Metabolite
EINECS	Contact for details

Quality Control

Our Enterodiol is produced under strict quality management protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive analytical and research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity confirmation, and impurity profiles. We support compliance with relevant research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.