Description

2-Cyano-3-Chloro-5-(Trifluoromethyl)-Pyridine is a high-value, multi-functional heterocyclic building block essential for advanced chemical synthesis. Its unique molecular structure, featuring cyano, chloro, and trifluoromethyl substituents on the pyridine ring, makes it a critical intermediate for creating compounds with tailored electronic and biological properties. This product is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances lipophilicity and metabolic stability.
• Material Science Research: Serves as a precursor for functionalized ligands in catalysis and for the synthesis of specialty polymers and electronic materials.
• Chemical Research & Development: Employed as a versatile building block in medicinal chemistry and process chemistry for structure-activity relationship (SAR) studies and route scouting.

Basic Information

Product Name	2-Cyano-3-Chloro-5-(Trifluoromethyl)-Pyridine
CAS No.	80194-70-3
Molecular Formula	C7H2ClF3N2
Molecular Weight	206.55 g/mol
Synonyms	3-Chloro-5-(trifluoromethyl)picolinonitrile; 2-Chloro-6-cyano-4-(trifluoromethyl)pyridine; 2-Cyano-3-chloro-5-trifluoromethylpyridine; 3-Chloro-5-trifluoromethyl-2-pyridinecarbonitrile; 2-Pyridinecarbonitrile, 3-chloro-5-(trifluoromethyl)-; 80194-70-3
EINECS	Contact for details

Quality Control

Our 2-Cyano-3-Chloro-5-(Trifluoromethyl)-Pyridine is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality attributes to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.