Description

4-(2-Fluorophenyl)-4-Piperidinecarboxylic Acid Ethyl Ester is a high-value fluorinated piperidine derivative, a crucial synthetic intermediate in modern pharmaceutical research and development. Its core value lies in its structural role as a versatile building block for constructing complex molecules with potential biological activity. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential central nervous system (CNS) active compounds and receptor modulators.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, leveraging the fluorophenyl moiety for enhanced bioactivity and stability.
• Chemical Biology & Medicinal Chemistry: Serves as a core scaffold for creating focused libraries in structure-activity relationship (SAR) studies and hit-to-lead optimization.
• Process Chemistry Development: Employed in route scouting and scale-up studies for the production of fluorinated active pharmaceutical ingredients (APIs).
• Academic Research: Utilized in universities and research institutes for investigating new synthetic methodologies involving fluorinated heterocycles.

Basic Information

Product Name	4-(2-Fluorophenyl)-4-Piperidinecarboxylic Acid Ethyl Ester
CAS No.	80142-03-6
Molecular Formula	C14H18FNO2
Molecular Weight	251.30 g/mol
Synonyms	Ethyl 4-(2-fluorophenyl)-4-piperidinecarboxylate; 4-(2-Fluorophenyl)-4-piperidinecarboxylic acid ethyl ester; 4-Piperidinecarboxylic acid, 4-(2-fluorophenyl)-, ethyl ester; Ethyl 4-(o-fluorophenyl)isonipecotate; 4-(2-Fluorophenyl)isonipecotic acid ethyl ester; 4-(o-Fluorophenyl)-4-piperidinecarboxylic acid ethyl ester; FPPE
EINECS	Contact for details

Quality Control

Our 4-(2-Fluorophenyl)-4-Piperidinecarboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports your R&D and scale-up processes with reliable, traceable materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.