Description

2-Chloro-α-Phenyl-3-Pyridinemethanol is a specialized organic compound featuring a pyridine core substituted with chlorophenyl and hydroxymethyl groups, making it a valuable chiral building block and intermediate. Its molecular architecture is critical for synthesizing complex molecules where precise stereochemistry and functional group compatibility are required. This compound is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-infective agents.
• Agrochemical Synthesis: Serves as a precursor in the manufacture of advanced pesticides and herbicides, leveraging its halogenated aromatic system.
• Ligand and Catalyst Development: Utilized in asymmetric synthesis as a precursor for chiral ligands or organocatalysts due to its stereogenic center.
• Material Science Research: Investigated as a monomer or functional additive for specialty polymers and advanced organic materials.
• Chemical Reference Standard: Supplied to analytical laboratories for method development, quality control, and regulatory compliance testing.
• Academic & Industrial R&D: Employed in exploratory chemistry for constructing complex heterocyclic frameworks in medicinal and synthetic chemistry programs.

Basic Information

Product Name	2-Chloro-α-Phenyl-3-Pyridinemethanol
CAS No.	80100-23-8
Molecular Formula	C₁₂H₁₀ClNO
Molecular Weight	219.67 g/mol
Synonyms	α-(2-Chlorophenyl)-3-pyridinemethanol; (2-Chlorophenyl)(3-pyridinyl)methanol; 2-Chloro-α-phenyl-3-pyridinemethanol; 3-Pyridinemethanol, α-(2-chlorophenyl)-; (3-Pyridyl)(2-chlorophenyl)methanol; 2-Chloro-α-phenyl-3-pyridylmethanol; (2-Chlorophenyl)(3-pyridyl)carbinol
EINECS	Contact for details

Quality Control

Our 2-Chloro-α-Phenyl-3-Pyridinemethanol is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets exacting research and production standards. A detailed Certificate of Analysis (COA) providing batch-specific data is supplied with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep the container tightly sealed to minimize contact with moisture and atmospheric oxygen.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee (or as specified)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.