Description

6-Chloro-Pyridine-2-Carbonyl Chloride is a high-purity, reactive chemical intermediate essential for advanced organic synthesis. Its bifunctional nature, featuring both a chloro-substituted pyridine ring and an acid chloride group, makes it a versatile building block for constructing complex molecular architectures. This compound is particularly valuable for researchers and manufacturers in the pharmaceutical and agrochemical industries seeking to develop new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and anti-infectives.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the pyridine moiety is a common pharmacophore.
• Ligand and Catalyst Development: Serves as a starting material for creating novel pyridine-based ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and organic electronic materials.
• Custom Synthesis and Contract Manufacturing: A critical building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	6-Chloro-Pyridine-2-Carbonyl Chloride
CAS No.	80099-98-5
Molecular Formula	C6H3Cl2NO
Molecular Weight	176.00 g/mol
Synonyms	2-Chlorocarbonyl-6-chloropyridine; 6-Chloropicolinoyl chloride; 2,6-Dichloropyridine-3-carbonyl chloride; Picolinoyl chloride, 6-chloro-; 6-Chloro-2-pyridinecarbonyl chloride; 6-Chloropyridine-2-carboxylic acid chloride
EINECS	Contact for details

Quality Control

Our 6-Chloro-Pyridine-2-Carbonyl Chloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, identity confirmation (IR, NMR), and impurity profiling. Certificates of Analysis (COA) are available for every batch upon request, supporting your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases, alcohols, and amines. Due to its reactivity as an acid chloride and sensitivity to moisture, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Recommended storage temperature: 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.