Description

Benzoic Acid, 4-Bromo-, 2,2,2-Trifluoroethyl Ester is a specialized fluorinated aromatic ester, identified by CAS number 80054-90-6. This compound is a valuable high-purity building block in advanced organic synthesis, prized for its unique combination of bromo and trifluoroethoxy functional groups. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the development of active pharmaceutical ingredients (APIs), particularly for introducing fluorinated aromatic motifs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides where the bromo and trifluoroethyl groups enhance biological activity.
• Liquid Crystal & OLED Material Precursor: Acts as a building block for fluorinated components in electronic display materials and organic light-emitting diodes.
• Polymer Modification: Employed to incorporate aromatic and fluorine-containing side chains into specialty polymers to alter thermal and surface properties.
• Cross-Coupling Reactions: The bromo substituent makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Sonogashira, or Buchwald-Hartwig couplings.
• Organic Synthesis Reagent: Utilized in academic and industrial research labs for constructing complex molecular architectures.

Basic Information

Product Name	Benzoic Acid, 4-Bromo-, 2,2,2-Trifluoroethyl Ester
CAS No.	80054-90-6
Molecular Formula	C9H6BrF3O2
Molecular Weight	283.04 g/mol
Synonyms	4-Bromobenzoic Acid 2,2,2-Trifluoroethyl Ester; 2,2,2-Trifluoroethyl 4-Bromobenzoate; p-Bromobenzoic Acid Trifluoroethyl Ester; 4-Bromo-benzoic acid 2,2,2-trifluoro-ethyl ester; α,α,α-Trifluoroethyl 4-bromobenzoate; Benzoic acid, 4-bromo-, 2,2,2-trifluoroethyl ester; Trifluoroethyl p-bromobenzoate
EINECS	Contact for details

Quality Control

Our production of Benzoic Acid, 4-Bromo-, 2,2,2-Trifluoroethyl Ester adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot is characterized by advanced analytical techniques including HPLC, GC, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. We support cGMP compliance for pharmaceutical intermediate use upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flames. The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.