Description

1-(Pyridin-4-Yl)-Piperidine-3-Carboxylic Acid is a high-value heterocyclic building block featuring a piperidine ring substituted with a carboxylic acid group and a pyridinyl moiety. This compound is essential for medicinal chemistry research and development, serving as a versatile intermediate for constructing complex pharmacophores. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers in the synthesis of novel active pharmaceutical ingredients (APIs) and other biologically active compounds.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and other therapeutic areas.
• Ligand Synthesis: Used in the preparation of complex ligands for catalysis and metal-organic frameworks (MOFs).
• Agrochemical Research: Serves as a building block for developing new active ingredients in crop protection chemicals.
• Chemical Biology Probes: Employed in the synthesis of molecular probes for studying biological pathways and target engagement.
• Academic & Industrial R&D: A valuable reagent for synthetic organic chemists in universities and corporate R&D laboratories exploring new chemical entities.

Basic Information

Product Name	1-(Pyridin-4-Yl)-Piperidine-3-Carboxylic Acid
CAS No.	80028-29-1
Molecular Formula	C11H14N2O2
Molecular Weight	206.24 g/mol
Synonyms	4-(3-Carboxypiperidin-1-yl)pyridine; 1-(4-Pyridyl)-3-piperidinecarboxylic Acid; 3-Piperidinecarboxylic acid, 1-(4-pyridinyl)-; 1-Pyridin-4-ylpiperidine-3-carboxylic acid; 1-(4-Pyridinyl)piperidine-3-carboxylic acid; 4-(3-Carboxy-1-piperidinyl)pyridine; 1-(Pyridin-4-yl)piperidine-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 1-(Pyridin-4-Yl)-Piperidine-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay, related substances, and residual solvents.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.