Description

Melatonin CAS NO 8041-44-9 is a naturally occurring indoleamine hormone, primarily synthesized by the pineal gland, that plays a critical role in regulating circadian rhythms and sleep-wake cycles. Its significance extends beyond physiological regulation, as it is a vital active pharmaceutical ingredient (API) and dietary supplement component with potent antioxidant properties. This product is essential for manufacturers in the pharmaceutical, nutraceutical, and cosmeceutical industries, where it is used to formulate sleep aids, support immune function, and develop anti-aging skincare products.

Application

• Pharmaceutical Active Ingredient (API): Core component in prescription and over-the-counter (OTC) medications for treating sleep disorders like insomnia and jet lag.
• Dietary Supplements & Nutraceuticals: Key ingredient in capsules, tablets, and gummies aimed at improving sleep quality, supporting immune health, and providing antioxidant support.
• Functional Food & Beverage Fortification: Used to enrich drinks, snacks, and other food products designed to promote relaxation and sleep.
• Cosmetic & Skincare Formulations: Incorporated into creams, serums, and lotions for its anti-aging, antioxidant, and skin-protective benefits.
• Veterinary Medicine: Employed in animal health products to manage sleep patterns and reduce stress in pets and livestock.
• Research & Biochemical Reagents: Serves as a standard and reagent in clinical studies, pharmacological research, and diagnostic kit development.

Basic Information

Product Name	Melatonin
CAS No.	8041-44-9
Molecular Formula	C₁₃H₁₆N₂O₂
Molecular Weight	232.28 g/mol
Synonyms	N-Acetyl-5-methoxytryptamine; Melatonine; Circadin; MLT; Pineal Hormone; NSC-113928; Regulin; 5-Methoxy-N-acetyltryptamine
EINECS	Contact for details

Quality Control

Our Melatonin is manufactured under strict quality management systems. We offer grades compliant with USP, EP, and FCC standards, ensuring suitability for pharmaceutical, nutraceutical, and food applications. Every batch undergoes rigorous analytical testing, including HPLC for assay and purity, residual solvent analysis, and heavy metals screening. A comprehensive Certificate of Analysis (COA) is provided with each shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to standard
Assay (HPLC)	98.0% - 102.0%
Melting Point	116°C - 120°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.