Description

(E)-2'-Hydroxychalcone is a high-purity organic compound belonging to the chalcone class of flavonoids, characterized by its distinct α,β-unsaturated ketone structure. This compound serves as a versatile and critical chemical intermediate and research chemical for the synthesis of more complex bioactive molecules. It is essential for organizations engaged in pharmaceutical R&D, agrochemical development, and advanced material science, where precise molecular building blocks are required.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel flavonoid derivatives with potential therapeutic applications.
• Biochemical Research: Used as a reference standard or probe in studies investigating biological pathways, enzyme inhibition, and antioxidant mechanisms.
• Agrochemical Development: Serves as a lead compound or intermediate for creating new plant growth regulators or protective agents.
• Organic Synthesis: A fundamental building block for constructing complex heterocyclic compounds and natural product analogs.
• Material Science: Investigated for its optical properties and potential use in organic electronic materials or sensors.
• Cosmeceutical Research: Studied for its UV-absorbing and skin-beneficial properties in advanced cosmetic formulations.

Basic Information

Product Name	(E)-2'-Hydroxychalcone
CAS No.	888-12-0
Molecular Formula	C15H12O2
Molecular Weight	224.25 g/mol
Synonyms	(E)-1-(2-Hydroxyphenyl)-3-phenylprop-2-en-1-one; 2'-Hydroxychalcone; (E)-2-Hydroxychalcone; o-Hydroxychalcone; 1-(2-Hydroxyphenyl)-3-phenyl-2-propen-1-one; NSC 407291; Benzylideneacetophenone, 2'-hydroxy-
EINECS	212-967-6

Quality Control

Our (E)-2'-Hydroxychalcone is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and industrial synthesis. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	88 - 92 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.