Description

3-(Hydroxymethyl)-6-Methyl-1,3-Diazaspiro[4.5]Decane-2,4-Dione is a specialized heterocyclic organic compound featuring a unique spirocyclic hydantoin structure. This molecular architecture makes it a valuable advanced pharmaceutical intermediate and a versatile building block for medicinal chemistry research. It is primarily utilized by pharmaceutical R&D and fine chemical synthesis sectors for developing novel active ingredients and complex molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting neurological and metabolic disorders.
• Medicinal Chemistry Building Block: Used to construct novel spirocyclic and heterocyclic scaffolds for high-throughput screening and structure-activity relationship (SAR) studies.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a core structural unit in the multi-step synthesis of proprietary APIs.
• Bioconjugation & Prodrug Development: The hydroxymethyl group provides a handle for conjugation, enabling the development of prodrugs and targeted drug delivery systems.
• Agrochemical Research: Investigated as an intermediate for creating novel pesticides and herbicides with specific modes of action.
• Material Science: Potential monomer or cross-linking agent for synthesizing specialty polymers with unique thermal or mechanical properties.

Basic Information

Product Name	3-(Hydroxymethyl)-6-Methyl-1,3-Diazaspiro[4.5]Decane-2,4-Dione
CAS No.	882-62-2
Molecular Formula	C10H16N2O3
Molecular Weight	212.25 g/mol
Synonyms	6-Methyl-3-(hydroxymethyl)-1,3-diazaspiro[4.5]decane-2,4-dione; 3-Hydroxymethyl-6-methyl-1,3-diazaspiro[4.5]decane-2,4-dione; Spirohydantoin derivative; 1,3-Diazaspiro[4.5]decane-2,4-dione, 3-(hydroxymethyl)-6-methyl-; Hydantoin, 3-(hydroxymethyl)-6-methylspiro[4.5]decane-
EINECS	Contact for details

Quality Control

Our 3-(Hydroxymethyl)-6-Methyl-1,3-Diazaspiro[4.5]Decane-2,4-Dione is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our production adheres to cGMP guidelines where applicable, ensuring reliability for your most demanding research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.