Description

3-(Chloromethyl)-1,3-Diazaspiro[4.5]Decane-2,4-Dione is a specialized heterocyclic building block featuring a reactive chloromethyl group attached to a spirocyclic hydantoin core. This compound is valued for its dual functionality, serving as a versatile intermediate in the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily sought by R&D chemists and process development scientists in the life sciences sector for constructing novel active pharmaceutical ingredients (APIs) and other high-value fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of spirocyclic compounds with potential biological activity.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides that incorporate the hydantoin moiety.
• Material Science: Serves as a monomer or cross-linking agent in the creation of specialty polymers with unique thermal or mechanical properties.
• Chemical Synthesis: The reactive chloromethyl group enables further functionalization, making it a versatile precursor for alkylation and nucleophilic substitution reactions.
• Ligand and Catalyst Development: Utilized in the design of novel chelating agents or organocatalysts due to its rigid spirocyclic structure.

Basic Information

Product Name	3-(Chloromethyl)-1,3-Diazaspiro[4.5]Decane-2,4-Dione
CAS No.	880-47-7
Molecular Formula	C9H13ClN2O2
Molecular Weight	216.66 g/mol
Synonyms	1,3-Diazaspiro[4.5]decane-2,4-dione, 3-(chloromethyl)-; 3-(Chloromethyl)spiro[imidazolidine-4,1'-cyclohexane]-2,5-dione; NSC 163049; Spiro[imidazolidine-4,1'-cyclohexane]-2,5-dione, 3-(chloromethyl)-; Chloromethylspirohydantoin; 3-Chloromethyl-1,3-diazaspiro[4.5]decane-2,4-dione
EINECS	Contact for details

Quality Control

Our 3-(Chloromethyl)-1,3-Diazaspiro[4.5]Decane-2,4-Dione is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.