Description

6-Azaspiro[2.5]Octane is a versatile and synthetically valuable nitrogen-containing spirocyclic building block. This compound is of significant interest in pharmaceutical research and fine chemical synthesis due to its unique constrained bicyclic structure, which can impart desirable pharmacological properties. It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key scaffold in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and other therapeutic areas.
• Medicinal Chemistry: Serves as a privileged structure for constructing compound libraries in drug discovery programs, enabling structure-activity relationship (SAR) studies.
• Agrochemical Synthesis: Used as a building block in the development of novel herbicides, fungicides, and insecticides with enhanced efficacy.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands and organocatalysts for asymmetric synthesis.
• Material Science Research: A precursor for novel polymers or organic frameworks with specific electronic or structural properties.
• Academic Research: A valuable reagent for methodological studies in organic synthesis, particularly in spirocycle formation and nitrogen heterocycle chemistry.

Basic Information

Product Name	6-Azaspiro[2.5]Octane
CAS No.	872-64-0
Molecular Formula	C7H13N
Molecular Weight	111.18 g/mol
Synonyms	6-Azaspiro[2.5]octane; 1-Azaspiro[2.5]octane; Azaspirooctane; Spiro[cyclopropane-1,6'-piperidine]; Hexahydrospiro[cyclopropane-1,6'-[2H]pyridine]; 1-Azoniabicyclo[4.1.0]heptane
EINECS	Contact for details

Quality Control

Our 6-Azaspiro[2.5]Octane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chromatographic purity assays and structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.