Description

Sodium tert-Butoxide is a powerful, non-nucleophilic base widely used in organic synthesis. Its core value lies in facilitating critical deprotonation and elimination reactions under mild conditions, offering advantages over more traditional bases. This reagent is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, where it is employed to construct complex molecular frameworks efficiently and selectively.

Application

• As a strong base for the deprotonation of weakly acidic C-H bonds in synthesis.
• Catalyst and reagent in the production of active pharmaceutical ingredients (APIs) and drug intermediates.
• Key reagent in the synthesis of agrochemicals, dyes, and fragrances.
• Used in elimination reactions, such as the formation of alkenes from alkyl halides.
• Employed in the synthesis of ethers and esters via Williamson ether synthesis and related reactions.
• Facilitates condensation reactions and the formation of carbon-carbon bonds in various organic transformations.

Basic Information

Product Name	Sodium tert-Butoxide
CAS No.	865-48-5
Molecular Formula	C4H9ONa
Molecular Weight	96.10 g/mol
Synonyms	2-Methyl-2-propanolate sodium; Sodium t-butoxide; tert-Butanol sodium salt; Sodium tertiary butoxide; t-BuONa; Sodium 2-methylpropan-2-olate; Sodium tert-butylate; Sodium tert-butanolate
EINECS	212-741-9

Quality Control

Our Sodium tert-Butoxide is produced and tested under stringent quality management systems to ensure batch-to-batch consistency and reliability. We offer various purity grades, including technical and high-purity reagent grades, to meet diverse application needs. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. This product is hygroscopic (moisture-sensitive) and a strong base. Store in a cool, dry, well-ventilated area, away from incompatible materials such as acids, oxidizing agents, and moisture. For long-term stability, storage under an inert atmosphere (e.g., nitrogen or argon) in a sealed container is recommended.

Specification

Item	Specification
Appearance	White to off-white powder or lumps
Identification (IR)	Conforms
Assay (Titration)	≥ 97.0%
Solubility (in THF)	Clear solution
Loss on Drying	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.